Northwestern University is conducting a Phase III clinical trial with Viromed Pharmaceuticals for an investigational drug (VM202) on painful, diabetic peripheral neuropathy in the legs and feet. This drug has been shown to be safe and effective at reducing pain caused by neuropathy through the generation of new blood vessels and nerves. The basic inclusion/exclusion …
Clinical Trial for Diabetic Peripheral Neuropathy Read More »
Summary of journal article reviewing the current state of diabetic peripheral neuropathy treatment: Painful diabetic peripheral neuropathy occurs in approximately 25% of patients with diabetes mellitus who are treated in the office setting and significantly affects quality of life. It typically causes burning pain, paresthesias, and numbness in a stocking-glove pattern that progresses proximally from …
Treating Painful Diabetic Peripheral Neuropathy: An Update Read More »
VM BioPharma, the United States division of ViroMed Co., Ltd. in Seoul, Korea, announced the first patient was dosed in the recently initiated Phase 3 clinical study evaluating VM202, a proprietary DNA-based biopharmaceutical, in patients with painful diabetic peripheral neuropathy (DPN). This is the first pivotal gene therapy trial specifically targeting the most common cause …
Underlying Cause of Diabetic Peripheral Neuropathy Targeted in Gene Therapy Trial Read More »
Peripheral neuropathy research study suggests even prediabetes could cause nerve damage. Peripheral neuropathy research results of a small study of people with tingling pain in their hands and feet have added to evidence that so-called prediabetes is more damaging to motor nerves than once believed. The report on the study was published online in JAMA …
On December 3, 2015, Astellas Pharma US, Inc. (the U.S. affiliate of Astellas Pharma Inc.), a R&D-driven global pharmaceutical company, invited the Foundation for Peripheral Neuropathy to present to a global team working on development of ASP3662 for patients with neuropathic pain (NP). This was an internal meeting, which included Ulf Tollemar, Executive Director, Development …
Emerging evidence suggests that the central nervous system (CNS) is a key contributor to the problem of painful peripheral nerve disease in people with diabetes, according to a special article in the February issue of Pain, the official publication of the International Association for the Study of Pain (IASP). Â READ MORE Source: MedicalPress
A new study led by researchers at McGill University in Canada recently revealed that peripheral neuropathy is associated with a mitochondrial dysfunction and a bioenergetic impairment. Mitochondria are small cellular organelles in the body responsible for the production of energy through the process of respiration. Mitochondria dysfunction can impair the cellular energy metabolism, affecting several …
Study Reports Peripheral Neuropathy is Associated with Mitochondrial Dysfunction Read More »
Research released earlier this summer shows that rats who received intra-muscular injections of mesenchymal stem cells (MSC’s are adult stem cells traditionally found in the bone marrow. but can also be isolated from other tissues including cord blood, peripheral blood, fallopian tube, and fetal liver and lung) 12 weeks after the induction of diabetes offered …
Stem Cells Show Promise as Treatment for Diabetic Neuropathy Read More »
Neuropathy is one of the most common long-term complications of diabetes mellitus (DM) and painful neuropathy can be challenging to treat. There is no consensus on optimal treatment and many current therapies are limited by their tolerability, the need for titration, drug-drug interactions, administration of multiple daily doses, or the invasive nature of surgical procedures …
Efficacy and Safety of Qutenzatm (8% Capsaicin Patch) Read More »
With more than 26 million people in the US living with diabetes, as reported by the Centers for Disease Control, approximately 60-70% of them will develop nerve damage called neuropathy at some point. New research has been published indicating that patients suffering with diabetic peripheral neuropathy (DPN) may experience a significant improvement in their pain …
