Advocating for PN research: the critical need for research dollars 

Peripheral neuropathy (PN) is vastly under-researched, despite its prevalence. While over 30 million Americans live with PN, the National Institutes of Health (NIH) funded less than $200 million in PN research from its $47 billion annual budget in 2024. That is less than $7 per PN patient.  

Neurological conditions are now the leading cause of ill health and disability worldwide. Neuropathy is the leading neurodegenerative condition in the world. Diabetic neuropathy is the fifth leading cause contributing to loss of health, and the fastest growing neurological condition. The number of people with diabetic neuropathy has more than tripled globally since 1990, making it imperative that PN gets the attention and research dollars that it deserves. 

NIH programs are a starting point 

PN research within the NIH is primarily conducted at the National Institute of Neurological Disorders and Stroke (NINDS). Other NIH institutes are working on related efforts, since PN is a common issue for those with diabetes or who receive chemotherapy. There is a critical need for coordination of PN research. A collaborative approach could reduce overall research costs and accelerate outcomes.

Past DoD funding success is something to build on 

Thanks to our efforts, PN has been listed as an eligible condition for the Defense Department’s Peer-Reviewed Medical Research Program (PRMRP) since 2021. That allows PN researchers across the country to submit projects for funding. Over the last four years, this has resulted in over $19 million in research grants. We want this amount to grow, to accelerate the research in the PN space. 

Biomedical research is key to the US economy 

We advocate for research funding for PN because the heart of our mission is to improve the lives of those living with this chronic condition. But research dollars are also crucially important to the US economy, and to maintaining our standing as the world leader in biomedical research. In fiscal year 2024, the NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide. The funding supports a broad range of institutions in states across the nation, including academic research centers, private companies, startups, and advocacy organizations.

What’s next?

We remain optimistic about the future of PN research. We know continuing to advocate for peripheral neuropathy research and spreading awareness of this chronic condition will produce better understanding of the condition and pave the way for more effective treatments and prevention.

Read more about our advocacy efforts and participate in future initiatives.